Because your Nutrition Plan

should be as unique as you are.

The Genate Prenatal Genetic Nutrition Test

The Genate Test was developed through over 30 years of Nutrition and Genetic Research funded by the NIH

Precision Gene Guided Nutrition | Genetics and Nutrition Metabolism

Genes are the blueprint for our health and development. We derive key nutrients through a series of chemical reactions that metabolize the food we eat into the building blocks our cells need to grow and multiply. These are pathways that synthesize and regulate nutrients within your body.

Gene errors (called SNPs) may cause inefficiencies in these pathways leading to deficiencies in the availability of important nutrition. This is particularly important during pregnancy when nutrient availability is critical to the development of the fetus.

Genate Starts with SNPs

SNPs (pronounced Snips) are variations in our genes . SNP is an acronym for Single Nucleotide Polymorphism. These variations might be called misspellings or mutations. The end result is that they change the way a gene functions. Whether it's eye or hair color, snps determine how cells work and how they are expressed. Metabolizing nutrition is no different.

The Genate test looks at your inherited genes and common misspellings in your genetic code that may affect how well you metabolize nutrition. If you can’t metabolize certain nutrients well, you will not be providing these nutrients to your baby. That’s why the test was developed, It helps you to build a nutrition plan that fits your genetic signature, so that you can make sure that you are doing your best when eating for two.

Nutrient metabolism is largely influenced by genetics

The Science Behind

The Genate Test

SNPs are variants that can change the way a gene functions (plural, pronounced Snips)

One carbon nutrients and fatty acids are particularly important during pregnancy

Genes regulating nutrient metabolism may have SNPs that can lead to reduced nutrient metabolic flow

These nutrients are critical building blocks for supporting healthy fetal brain development

Knowing if you have SNPs in these pathways can help you personalize your nutritional needs during pregnancy

SNPs are variants that can change the way a gene functions (plural, pronounced Snips)

One carbon nutrients and fatty acids are particularly important during pregnancy

Genes regulating nutrient metabolism may have SNPs that can lead to reduced nutrient metabolic flow

These nutrients are critical building blocks for supporting healthy fetal brain development

Knowing if you have SNPs in these pathways can help you personalize your nutritional needs during pregnancy

Test Results

What’s Included:

Genate Nutrient Metabolism Summary Score

The Genate test algorithm provides a comprehensive polygenic risk score based on extensive research into the functional genes that interdependently affect one carbon metabolic efficiency. Inefficient one-carbon nutrient metabolism can impact gestation and pregnancy outcomes as well as your child’s brain composition. Knowing whether or not you have inefficiencies can help you make changes to your diet to support your unique needs. As a genetic variant detection and health risk assessment system, its clinical validity is established by decades of research identifying the functional genes affecting nutrient metabolism in one carbon nutrition.

Identification Of Your Metabolic Pathway Roadblocks

The Genate Test reports on the following metabolic pathways and genes:

Folate and Choline Metabolism

Genes: MTHFR and MTHFD1

Phosphatidylcholine and Choline Synthesis

Genes: PEMT, CHK, and SLC44A1

DNA Methylation

Genes: MTR and BHMT

Choline and Betaine Metabolism

Genes: CHDH

Fatty Acid Metabolism (DHA)

Genes: PNPLA3, APOC3, FADS2, and SCD

Gene Variants & Nutrients Table

The Genate Report provides information on genetic variants that address the metabolism of the following nutrients: choline, folate, DHA, betaine, A, B6, B12, C, D, K, riboflavin, calcium, iron, and magnesium.

Unique One Carbon Nutrient Recommendations

Personalized Precision nutrition recommendations can help you tailor your meal planning and supplement needs that are unique to your particular needs, not based on a one size fits all approach.

Additional Vitamins and Minerals Recommendations

Individual nutrient cards provide you with insights into areas where you should increase your dietary intake. Work with an RDN on staff to help you support your meal planning and supplement needs and/or use our diet questionnaire and resources to learn how much more of a given nutrient you need and where to find it.

From Nutrition Research to Advanced Genetic Algorithms

The Genate Test analyzes over 300 SNPs across 5 metabolism pathways that contribute to the breakdown and the synthesis or transmission of important One-Carbon and Fatty Acid nutrients to babies during pregnancy and breastfeeding.

The algorithm is exclusive and comprehensive. Genate evaluates 5 interdependent metabolic pathways to provide you with true precision nutrition.

The Genate Report addresses efficiencies in metabolizing the following nutrients important for Cognitive Development:

Choline, Folate, DHA, B12, Betaine, & Oleic Acid

The test will also report on genes and SNPs associated with the following nutrients:

Vitamins A, C, D, K, Riboflavin, B6, Calcium, Iron, & Magnesium

Discover your personalized nutrition plan with the Genate test →

Discover your personalized nutrition plan with the Genate Test

Get your test

One Carbon Pathways and Genetic Variation

Think about metabolic pathways like a highway. Similar to highway construction causing a traffic jam, genes with SNPs can slow down and even cause roadblocks in your body’s metabolism of nutrition. These blockages can affect the nutrients needed for many functions in the body.

The Genate Test evaluates multiple SNPs across related pathways, rather than one at a time, by using a sophisticated algorithm that identifies genetically caused roadblocks so you and your health care provider can make decisions to support optimal nutrition for you and your baby during pregnancy.

Cognitive Benefits of Elevated levels of One Carbon Nutrition – Choline and Sustained Attention in School Aged Children

Children born to high choline consuming mothers showed greater attention control and signal detection performance.

They also showed a superior ability to maintain correct signal detections across the 12-min session, indicating improved sustained attention.

Reference: Bahnfleth CL, et al. FASEB J2022; 36(1): e22054;

Prenatal Vitamins

The science of nutrition for pregnancy is advancing all the time and that is also true for prenatal vitamins. There are lots of differences between pre-natal vitamins. There are also lots of differences between people and the nutrition they metabolize well and the nutrition they don’t metabolize well.

You may, however, have genetic challenges that make it difficult for you to efficiently metabolize these important nutrients even with a great varied diet. The only way you can understand if your prenatal nutrition is meeting the cognitive development needs of your developing baby is by taking a genetic test. Obtaining adequate levels of DHA, Choline, Folate, B12, B6, Vitamin A, C, D, K, magnesium, calcium and Iron is dependent on your genetics and how SNPs effect your metabolism of these nutrients.

Unless you take a genetic test, you just won’t know whether your diet and prenatal meets your needs. A precision nutrition plan focuses on planning your nutrition around your genetic signature, and that may include a prenatal vitamin with advanced ingredients and higher values of nutrition. Not sure where to start? Try our Essential Prenatal Vitamin first to build a strong foundation of health, then discover what customizations you may need with Genate.

Learn how to tailor your pregnancy nutrition to your unique genetic signature →

Learn how to tailor your pregnancy nutrition to your unique genetic signature

Get your test

Take the Genate Test

Learn how to tailor your pregnancy nutrition to your unique genetic signature.

Get Your Test

Meet the Genate Team

We’re passionate about improving human health through precision nutrition – helping moms like you make personalized, proactive decisions to positively impact your prenatal journey.

Developed by researchers from: