The Genate test algorithm provides a comprehensive polygenic risk score based on extensive research into the functional genes that interdependently affect one carbon metabolic efficiency. Inefficient one-carbon nutrient metabolism can impact gestation and pregnancy outcomes as well as your child’s brain composition. Knowing whether or not you have inefficiencies can help you make changes to your diet to support your unique needs. As a genetic variant detection and health risk assessment system, its clinical validity is established by decades of research identifying the functional genes affecting nutrient metabolism in one carbon nutrition.

The Genate Test reports on the following metabolic pathways and genes: 

Folate and Choline Metabolism

Genes: MTHFR and MTHFD1

Phosphatidylcholine and Choline Synthesis

Genes: PEMT, CHK, and SLC44A1

DNA Methylation

Genes: MTR and BHMT

Choline and Betaine Metabolism

Genes: CHDH

Fatty Acid Metabolism (DHA)

Genes: PNPLA3, APOC3, FADS2, and SCD

The Genate Report provides information on genetic variants that address the metabolism of the following nutrients: choline, folate, DHA, betaine, A, B6, B12, C, D, K, riboflavin, calcium, iron, and magnesium.

Personalized Precision nutrition recommendations can help you tailor your meal planning and supplement needs that are unique to your particular needs, not based on a one size fits all approach. 

Individual nutrient cards provide you with insights into areas where you should increase your dietary intake. Work with an RDN on staff to help you support your meal planning and supplement needs and/or use our diet questionnaire and resources to learn how much more of a given nutrient you need and where to find it.